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The Autosomal Recessive disease, Cystic Fibrosis (CF), runs in Jill’s family. Jill is unaffected. Based on...

The Autosomal Recessive disease, Cystic Fibrosis (CF), runs in Jill’s family. Jill is unaffected. Based on this data, select which of the following statements could be True?

A.

If Jill’s Paternal Aunt is affected and her Paternal Grandparents are unaffected. There is a 2/3 probability her father is a Carrier
B.

In the future, Jill’s parents have another child and that child has CF. Therefore, her parents have a 100% probability of being Carriers
C.

Jill could never produce a child that is affected with CF
D.

Only, A and B are True
E.

A, B, and C are True
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Answer #1

1) The Autosomal Recessive disease, Cystic Fibrosis (CF), runs in Jill’s family. Jill is unaffected. Based on this data, select which of the following statements could be True?

D) A and B are true

Cystic fibrosis is inherited in an autosomal recessive manner. Our genes come in pairs, with one copy inherited from each parent.When both parents are carriers for a recessive disorder, each child has a 1 in 4 chance of inheriting the two changed gene copies.

If Jill’s Paternal Aunt is affected and her Paternal Grandparents are unaffected. There is a 2/3 probability her father is a Carrier

In the future, Jill’s parents have another child and that child has CF. Therefore, her parents have a 100% probability of being Carriers so the both A and B are true

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