Which of the following classes of antibiotics is particularly effective against anaerobes?
Quinolones (e.g.) nalidixic acid) |
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Nitroimidazole (e.g. metronidazole) |
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Fluroquinolones ( e.g. ciprofloxacin, norfloxacin) |
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Cephalosporins (e.g. cephazolin |
Nitroimidazole (eg : metronidazole) is very effective against anaerobic bacteria.
because this class of antibiotics causes the cell death of bacteria by means of destruction of protien synthesis for DNA formation of bacteria.(bactericidal action)
quinolones , fluroquinalones and ciprofloxacin are having bacteriostatic activity in their cells. That means bacteria won't die , instead these Medicines make bacteria inactivate and inhibit their replication .
so metronidazoles are effective for anaerobic bacterial infection.
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