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Which lab value indicates an increased risk for an infusion reaction for a patient with lymphoma...

Which lab value indicates an increased risk for an infusion reaction for a patient with lymphoma who is scheduled to receive rituximab?

a. ANC 6,500mm3

b. platelet count 100,000mm3

c. circulating lymphocytes 30,000mm3

d. hematocrit 35%

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Answer #1

Option (c) , circulating lymphocytes 30,000 mm3

As , RITUXIMAB can cause severe fatal , infusion related reaction .Severe reaction typically occured during the first infusion with time to onset of 30 to 120 minutes. That s why it is closely monitor the following patient ;- those with pre- existing cardiac or pulmonary conditions and those who are experienced prior cardiopulmonary adverse reaction and especially those with high numbers of circulating malignant cells like lymphoma ( above or equal to 25,000/mm3) .

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