Question

An order for a 66-lb child is for amoxicillin 20 mg/kg/d in three divided doses. The available medication is 150 ml of amoxicillin oral suspension 250 mg/5 mL after reconstitution with 105 mL of distilled water.

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What is the powder displacement of the reconstituted medication?

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What is the strength of one dose for the child in mg?

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What volume of medication should be administered per dose?

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How many full doses are in the reconstituted form?

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Is one bottle sufficient for a 10-day supply of medication?

Answer 1

1. Displacement is defined as the occupation by submerged body of a volume which would otherwise be occupied by a fluid.  

2. Body weight =66lb=22.94 kg

Required dose= 20mg/kg/day

Total dose per day=20×22.94= 458.8mg/day

Total dose in mg per dose= 458.8÷3= 152.93 mg/dose

3.Total volume per dose= (5÷250)×152.93= 3.0586ml

4. Total mg in reconstituted form=(250÷5)×150= 7500mg

So total full dose= (7500÷152.93)= 49.04

5.yes, one bottle is sufficient for 10 days medicatio.