Summarize this passage.
Bisphenol-A (BPA) is a widespread endocrine disruptor that produces insulin resistance and alterations in pancreatic β-cell function [1]. It has been suggested that together with other endocrine disrupting chemicals (EDCs), BPA constitutes a risk factor for type 2 diabetes and other metabolic disorders [2]–[4]. Recent work shows the association between increasing urinary BPA levels and Diabetes Mellitus. A 12.8% of diabetic patients show high BPA levels in urine samples (4.20 ng/ml or 18 nM) [5]. Moreover an association between urinary levels of BPA, obesity and insulin resistance in middle-aged and elderly chinese adults has been recently described [6]. The range of BPA levels found in humans is from 0.7 to 20 nM [7], [8]. To support the evidence that BPA may be a risk for the development of diabetes it is critical to study its effect on human tissues involved in glucose and lipid metabolism, including the endocrine pancreas which is key in glucose homeostasis.
This passage says that Bisphenol is one endocrine disputor that
is widespread and it causes insulin resistance and alterations in
the pancreatic B cell fuctions.
it also has a risk of type 2 diabetics and other metabolic
disorders.
and there is increase in BPA and diabetics mellitus in recent works
of urine samples and to support the evidence that BPA may be a risk
for the development of diabetes it is critical to study its effect
on human tissues involved in glucose and lipid metabolism,
including the endocrine pancreas which is key in glucose
homeostasis.
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