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QUESTION 12 Your 90 year-old hospitalized patient has developed a severe systemic fungal infection and will...

QUESTION 12 Your 90 year-old hospitalized patient has developed a severe systemic fungal infection and will be started on amphotericin, a highly nephrotoxic drug. Which of the following should be obtained before beginning therapy? a. serum calcium b. serum creatinine c. creatinine clearance d. a CBC (complete blood count)

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Answer #1

d. a CBC (complete blood count)

Explanation:

-Amphotericin B is the highest important polyene.

-It applies its antifungal result by requisite to ergosterol in the fungal cell film, changing membrane permeability.

- The mutual drug effects on the kidneys are a quantity reliant on reduction in glomerular percolation proportion, uremia, potassium and magnesium degenerative, renal tubular acidosis and polyuria.

-Nephrotoxicity is typically revocable but enduring damage of renal function is connected to great total amount.

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