Question

Post a description of the patient case from your experiences, observations, and/or clinical practice from the last 5 years.

Then, describe factors that might have influenced pharmacokinetic and pharmacodynamic processes of the patient you identified.

Finally, explain details of the personalized plan of care that you would develop based on influencing factors and patient history in your case. Be specific and provide examples.

Answer 1

b)

Pharmacokinetics describes what the body does to the drug through absorption, distribution, metabolism, and excretion, whereas pharmacodynamics describes what the drug does to the body.

it is essential to consider individual patient factors that might impact the patient’s pharmacokinetic and pharmacodynamic processes. These patient factors include genetics, gender, ethnicity, age, behavior (i.e., diet, nutrition, smoking, alcohol, illicit drug abuse), and/or pathophysiological changes due to disease.

Pharmacodynamics (sometimes described as what a drug does to the body) is the study of the biochemical, physiologic, and molecular effects of drugs on the body and involves receptor binding (including receptor sensitivity), postreceptor effects, and chemical interactions.

There are four factors that will affect the pharmacokinetic drugs test: water-solubility; fat-soluble; dissociation degree and molecular weight. Pharmacokinetic is a quantitative study of drugs in the body absorption, distribution, metabolism and excretion of the law.

Pharmacokinetics of a drug depends on patient-related factors as well as on the drug's chemical properties. Some patient-related factors (eg, renal function, genetic makeup, sex, age) can be used to predict the pharmacokinetic parameters in populations.