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A 55-year-old man presents to his primary care physician complaining of gross hematuria and right loin...

A 55-year-old man presents to his primary care physician complaining of gross hematuria and right loin pain. Physical examination reveals a flank mass. The complete blood count (CBC) reveals a hemoglobin level of 21 g/dL and polycythemia. Ultrasound shows a 6.0-cm mass at the upper pole of the right kidney.

What is most likely the diagnosis?

Where do these tumors arise from?

What is the most likely explanation for this patient's polycythemia?

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Answer #1

Answer-

• Diagnosis - Kidney cancer (renal cell carcinoma)

• It start in the Kidney. It starts when cells in the kidney grow out of control and crowd out normal cells. This makes it hard for the body to work the way it should. Cancer cells can spread to other parts of the body.

tumor marker for kidney cancer In conclusion ESR and fibrinogen were thought to be useful for screening renal cell carcinoma patients ESR, CEA, haptoglobin, fibrinogen and C3 for estimation of staging, and ESR, CEA, haptoglobin and C3 for estimation of prognosis.

• Despite elevated EPO receptor and serum levels, a significant proportion of renal cell carcinoma patients exhibit anemia and polycythemia, which may result from EPO hyporesponsiveness, iron deficiency, and chronic inflammation

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