1. Ibuprofen 10 mg/kg every 6 hours is prescribed for a 6 month old infant with fever. The infant weighs 8 kg. Your bottle of ibuprofen is labeled 100 mg / 5 mL. How many mL will you give the infant for each dose?
2. Cephalexin 25 mg/kg/day PO divided q 8h is ordered for a child with a beta-hemolytic streptococcal infection. The child weighs 18 kg. Your bottle of Cephalexin is labeled 250 mg / 5 mL. How many mL will you give the child every 8 hours?
1.Given
Order: Ibuprofen
Frequency:4 times a day
Weight:8kg
Dose:10mg/kg
As 1kg=10mg
Then 8kg=??mg
Cross multiply and divide
=8×10/1
=8×10
=80mg
Available:100mg/5ml
Then 80mg=??ml
Cross multiply and divide
=80×5/100
=400/100
=4
Ans: The infant has to be given 4ml per dose
2.Given
Order:Cephalexin
Frequency:3times a day
Route:Per oral
Dose:25mg/kg/day
Weight:18kg
When 1kg=25mg
Then 18kg=??mg
Cross multiply and divide
=18×25/1
=18×25
=450mg
Therefore dose is 450mg/day
To calculate for 1 dose divide by 3
=450/3
=150
150mg/dose has to be given
Available:250mg/5ml
Then 150mg=??ml
Cross multiply and divide
=150×5/250
=750/250
=3
Ans: The child has to be given 3ml every 8 hour
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