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Distinguish between hepatitis B surface antigen and antibody findings for immunized versus chronic disease patients?

Distinguish between hepatitis B surface antigen and antibody findings for immunized versus chronic disease patients?

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#. Difference between HBsAg and anti -HBs

Hep B surface antigen Marker (HBsAg)

Protein on the surface of the HBV that can be detected in high levels in serum during acute or chronic infections.

Indicates that the person is infectious.

Body produces antibodies to HBsAg as part of the normal immune response

HBsAg is the antigen used to make the hep B vaccine

It is negative in vaccinated individuals

#. Hep B surface antibody Marker (anti-HBs)

Presence indicates recovery and immunity from HBV

Will also develop in a person who has been successfully vaccinated against hep B

It is negative in individuals with acute or chronic infection ( hepatitis)

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