Question

Redness and tenderness of skin that becomes widespread, followed by painful blisters, bullae, and sloughing of skin describes which of the following conditions? Atopic dermatitis Tinea corporis Impetigo Staphylococcal scalded skin syndrome

Answer 1

Correct answer: Staphylococcal scaled skin syndrome

Explanation:

• This is a type skin infection caused by the phage group 2 staphylococci, (strain 71 and 55)
• It is caused by exfoliative toxin ETA and ETB
• The toxins are proteases which targets the desmoglein - 1. This leads to seperation of the epidermal layer beneath the granular layer.
• The symptom starts with fever, widespread redness of skin
• After 24 hours fluid fllled blisters and bullae develop.
• The top layer of the skin peels off like a sheet.
• Nikolsky sign is postive ( gentle stroking of skin leads to exfoliation of the skin