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Give one example of Full human MABs produced by transgenic mouse technology and its clinical use?

Give one example of Full human MABs produced by transgenic mouse technology and its clinical use?

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Answer #1

MABs is nothing but monoclonal antibody. MABs are used for the treatment of many solid tumors, including renal cell carcinoma, colorectal, lung, and breast cancer.

Example of Full human MABs produced by transgenic mouse technology:

  1. Bevacizumab
  2. Cetuximab (Which is an epidermal growth factor receptor (EGFR) inhibitor)
  3. Panitumumab

1. Clinical use of Bevacizumab:

  • It is used in treatment of several types of cancer.
  • It is used to treat specific eye diseases.

2. Clinical use of Cetuximab:

  • It is used in the treatment of metastatic colorectal cancer
  • It is used in the treatment of metastatic non-small cell lung cancer
  • It can be also used to treat head and neck cancer.

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