When is an RCT not the most appropriate or suitable research design to answer a question about intervention effectiveness?
a. When it is not ethical to randomly allocate study participants to experimental or comparison/control groups.
b. When it is not practical to conduct an RCT because the outcome is very rare and a very large number of participants would need to be enrolled in the trial.
c. When it is not feasible to conduct an RCT because the outcome may take a very long time to manifest.
d. All of the above
Option d - All of the above
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