Question

Acetazolamide sodium is available in 500-mg vials to be constituted to 5 mL with sterile water for injection before use. The dose of the drug for children is 5 mg/kg of body weight. How many milliliters of the injection should be administered to a child weighing 25 lb?

Answer 1

Step 1: Convert pounds to kg (1 kg = 2.2 pound)

so, 25 lb = 25 / 2.2 = 11.36 kg

Step 2: Calculate dose to be administered for the chid.

5mg/kg is the prescribed dose.

Prescribed dose for a child weighing 11.36 kg

= 5 * 11.36

= 56.8

Approximately 57mg is the prescribed dose.

Step 3: Calculate the prescribed dose in ml.

The available dose is 500 mg per 5 ml.

Desire dose = Prescribed dose/Amount in hand * Quantity

= 57 / 500 * 5

= 0.114 * 5

= 0.57 ml

= 0.6 ml ( rounded off to the nearest value)

For a child weighing 25 pounds, 0.6ml of Acetazolamide sodium should be administered.