TRASTUZUMAB
TYPE OF ANTIBODY - It is a monoclonal antibody used to treat breast cancer and stomach. IT ACTS ON HER2 receptor
Mechanism of action - Basixally cells in breast and stomach grows by Her2 receptor and in cancer this receptor are upregulated. Trastuzumab binds with this receptors and down regulates the cell division and thereby helping controlling growth of cancer cells.
one example of a biosimilar for “Trastuzumab” - ABP 980 is a biosimilar for trastuzumab used for breast cancer.
Which action is appropriate in prescribing “Trastuzumab”: the doctor or the clinical pharmacist. Explain why - Doctor is the right person to prescribe trastuzumab as this drug is not for all breast cancer but it is specifically for HER2 receptor positive breast cancer which doctor would know and not the pharmacist.
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