Question

Researchers conducting a large clinical trial (N=2243) reported a mean hemoglobin of 11.8 at baseline and...

Researchers conducting a large clinical trial (N=2243) reported a mean hemoglobin of 11.8 at baseline and after applying an intervention, a hemoglobin of 12.0 at the conclusion of the study. After statistical analysis, this proved to be a statistically significant difference. When studies show statistical significance in areas that have no real clinical significance, how would you apply the study to practice.

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Answer #1

While statistical significance indicates the reliability of the study results, clinical significance reflects its impact on clinical practice. ... The “P” value, frequently used to measure statistical significance, is the probability that the study results are due to chance rather than to a real treatment effect.

As it improved the hemoglobin value after finding the output it can be done on the huge population and make it possible to bring out a Big interventions

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