Question

What do chloramphenicol derivatives, macrolides, and lincosamides target?

30 s ribosomal subunit

Cell wall

50s ribosomal subunit

Nucleus

QUESTION 7 Combination of bactericidal drugs is ________.

Antagonistic

Synergistic

Additive

QUESTION 8 What do tetracyclines and aminoglycosides target?

30 S ribosomal unit

Cell wall

Nucleus

Cell membrane

QUESTION 9 Which antimicrobials act on the bacterial cell membrane, changing the permeability, Select all that apply.

Tetracycline

Polymyxin

Vancomycin

Gentamicin

Answer 1

6) 50s ribosomal subunit

The chloramphenicol derivatives,macrolides,and lincosamides targets on 50s ribosomal subunit .

* The chloramphenicol derivatives will diffuses through the bacterial cell wall and binds to the 50s ribosomal subunit .

* The macrolides will inhibit the protein synthesis in the bacteria by reversibly binding to the P site of 50s ribosomal subunit .

* The lincosamides binds to the 50s ribosomal subunit at the site which is closely releated to that at which the macrolide act .

7