Question

All of the following is/are factors/events known to induce apoptosis EXCEPT:
Select one:
a. Genotoxic stress (severe irreparable damage to DNA)
b. Cellular injury following severe protein misfolding.
c. FAS activation following FAD binding to FASL
d. Anoxia
e. C+D

Which of the following is an example of of an acute neuropathic pain?
Select one:
a. Hand burn after touching a stove.
b. Exposure to a caustic alkaline solution.
c. Increased levels of circulating substance-P and prostaglandins.
d. Joint and chest pain in an individual suffering from opioid withdrawal reaction
e. None of the above

Which of the following symptoms is not usually indicative of a right-sided heart failure?
Select one:
a. Hepatomegaly
b. Cough
c. Ascites
d. Palpitations
e. B+D

Answer 1

1-Genotoxic stress triggers endoplasmic stress and unfolded protein response leads to apoptosis.

FasL expression leads to fast transsuction of apoptosis.

Anoxia activates proapoptosis BCL 2 proyein and intiate apoptosis.

Hence the option B cellular injury do not cause apoptosis.

Option B ia the correct answer.

2.Acute neuropathic pain isvery difficult to identify and treat ,if untreatd it leds to permennt disability and pain.It is characterised by butning,shoothing pain and tingling sensation.

Acute neuropathic pain is caused by chronic medical comsitions,injury and burns

Hence the option A is the answer

3 .Hepatomegaly is most important sign in patient with right side heart failure.

Cough and shortness of breath also occurs.

In this right side of the heaet is not able to pumb blood ,and blood returns to the body .This may result in perioheral oedema and swelling im abdomen ,mainly Gi tract and liver leads to ascitis.

Hence the option D palpitaion is not the sign of right side heart failure.

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