Question

1. Mr. Smith was diagnosed with sickle cell anemia. He has an ulcer in the medial side of his ankle. What are your initial reactions and observations of the case? How would the condition of the red cells contribute to what the patient suffers from

2. How would you describe inflammation? How do you recognize that Mr. Smith has an inflammatory response? Is inflammation always bad? Do you know of any white cell disease that reduces our inflammatory response?

3. Mr. Smith is allergic to penicillin and iodine. What do you know about allergies? What type of hypersensitivity is it?

Answer 1

In this type of patient the ankle ulcer is the long recognized complication SCD.

The leg ulceration and inflammation occurs in areas with less cubcutaneous fat,thin skinand decreased blood flow.The skin ulcers may be classified as acute and chronic according to the duration it is the disabling complication of SCD.

The inflammation is not always bad it is the sign of the disease and the inflammation it self has the ability to destroy the microbes by the inflammatory process, he is allergic to penicillin so we can administer the drug clindamycin this drug is effective for this type of infections.

The penicillin hypersensitivvity is comes under Type 1 hypersensitivity reaction the IgE antibodies decreases over time.

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