Question

your patient has liver and kidney disease. he is given a medication with a half life...

your patient has liver and kidney disease. he is given a medication with a half life of 30 hours. You expect the duration of this medication to do what, and why?
a. increase
b. decrease
c. remain unchanged
d. dissipate
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Answer #1

The liver and the kidney are the two vital organs helping the body to clear wastes and toxins by its metabolism. When there is a disease in these organ the metabolism is affected. As a result if it is a drug then it is retained or it binds to the plasma protein and hence increasing the half life of the drugs .

The half can decrease when the function of the liver and kidney are more than the normal in elimination

It remain unchanged in case if liver or renal disease

The drugs remain in the blood but does not dissipate

Ans:a.increase

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