Question

Discuss advancements in research that link genetic factors to schizophrenia

Answer 1

Answer)-RECENT RESEARCH ADVANCEMENT- The genetic etiology of schizophrenia, a common and debilitating psychiatric disorder, is supported by a wealth of data. Review of the current findings suggests that considerable progress has been made in recent years, with a number of chromosomal regions consistently implicated by linkage analysis.

Three groups have shown linkage to 1q21–22 using similar models, with HLOD scores of 6.5, 3.2, and 2.4. Other replicated loci include 13q32 that has been implicated by two independent groups with significant HLOD scores (4.42) or NPL values (4.18), and 5p14.1–13.1, 5q21–33, 8p21–22, and 10p11–15, each of which have been reported as suggestive by at least three separate groups.

A greater understanding of disease mechanisms and the application of pharmacogenetics should also lead to improvements in therapeutic interventions.