Question

A karyotype would be useful in detecting:

A. a point mutation.

B. congenital birth defects.

C. which allele is present on a specific chromosome.

D. a translocation of one arm of a chromosome.

Answer 1

Option A: A point mutation affects only a single neucleotide. It is detected generally by .PCR based amplication tests,DNA microarray technology etc.

Option B: Congenital birth defects screening can be done through amniocentesis, chronic villus sampling and ultrasound

Option C: An allele is located on specific positions on specific chromosomes and its alternative form of a gene. Allelle Specific Amplification tests (AS -PCR). helps to detect them.

Correct option is Option D: translocation occurs when a part of chromosome breaks and reattaches to another. This can be detected using Karyotyping test. Karyotype tests detects the characteristics of the chromosomes (like their number,size and shape)