Question

Aminopterin
a. Non of the answers
b. Precursor for DNA synthesis
c. Brings fusion of two cells
d. Powerful toxin which blocks the metabolic pathway

Answer 1

D) powerful toxin which blocks the metabolic pathway.

b) precursors of dna synthesis - not a precursor because , it binding affinity for dihydrofolate reductase effectively blocks tetrahydrofolate synthesis. This results in the depletion of nucleotide precursor and inhibition of DNA , rna and protein synthesis .

c) brings fusion of two cells- false . Because it is a 4- amino derivative of folio acid , is an antineoplastic drug with immunosuppressive properties often used in chemotherapy.