Question

1.If a person is severely dehydrated, which type of IV solution (hypotonic/isotonic/hypertonic) would replace intracellular fluid lost from cells? Explain it.

2. Edema refers to tissue swelling, and this occurs when fluid is drawn out of the blood plasma and into the interstitial fluid of the tissues. One symptom of certain forms of thyroid disease results in an overaccumulation of proteins in the interstitial fluid.
a. Based on the fact that proteins are typically large, charged and polar, do you predict that they would be able to easily cross cell membranes and tissue membranes? Explain by discussion characteristics of cell membranes.

b.In this scenario of thyroid disease, where would the higher concentration of osmotically active particles be?

c.Based on your answer to “b,” which way would the water move? Explain using the definition of osmosis.

d.Would this scenario result in edema?

Answer 1

Question no 1

Hypotonic solution is to be administered to the patient as when this fluid is taken in then the movement of fluid from higher solute concentration to lower solute concentration will occur .

When fluid is lost in the intracellular space the solutes concentration over there will be High and when hypotonic solution is administered the solute concentration will decrease in the extracellular space . This will lead to the movement of fluid from low solute concentration that is from extracellular space to the intracellular space . Thus fluid replacement in the cell will take place .

If hypertonic solution is Given the cell volume will further deteriorate as the concentration of solute will increase in the extracellular space and lead to movement of fluid outside of the cells that is to higher solute concentration

If isotonic solution is administered then movement will not occur