if 200 mg of a drug results in plasma concentration of 10 mg/L what is the calculated volume of distribution (VD) ?
Answer: Volume of distribution (VD) is a measurement of how a drug is dispersed in the body related to the measured plasma concentration .It is calculated by the amount of the drug in the body divided by the plasma concentration.
VD iused to determine the loading dose of a drug,the half-life of a drug,medication clearance,and drug toxicity.
The formula to calculate volume distribution (VD)
VD = Total amount of drug in the body / Drug blood plasma concentration
Total amount of drug = 200 mg
Plasma concentration = 10mg/L
200/10 = 20L
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