Question

Describe one of the four processes of pharmacokinetics?
in the first chapter ( pharmacology for the surgical technologist . Katherine C. Snyder / Chris Keegan. Fourth addition)

thank you

Answer 1

Pharmacokinetics is simply defined as the process going on in the body once the drug is taken

this includes

1.Drug Absorption

2.Drug distribution

3.Drug metabolism

4.Drug excretion

DRUG EXCRETION

Drug excretion is a process by which the rwmaining particles of the drug after is absorption leaves the body through excretory fluid like sweat,urine and bile ,solid like. feaces and gases like expired air.

Each drug has there own way of excretion.Urinary excretion is the usual route of elimination for low molecular weight drugs that are not metabolised and are sufficiently water-soluble to avoid reabsorption from the renal tubule. And even the small water-soluble metabolites that enter the bloodstream after metabolism in the liver or other organs are also excreted by this route.
Faecal excretion is the preferred route of elimination for larger molecular-weight drugs, including those that are conjugated with glucuronide in the liver, and any drugs that are not absorbed are also excreted through feaces

Molecules of drug or metabolite that enter the bile are also eliminated in the faeces