Question

1. D5W solution is being infused at 50 ml/hr. D5W stands for 5% dextrose (glucose) in water.
How much glucose is the patient going to receive after 10 hours of infusion?

2. A Total Parenteral Nutrition (TPN) solution contains 8.25% amino acids in it.
If the patient needs 75 grams of protein a day, how much of the TPN solution should the patient receive per day?
What should be the infusion rate, if we need to infuse this solution within 20 hours?

3. An IV solution containing 0.025% of Drug X has been infusing since 6 AM at 100 ml/hr.
How much drug X will the patient receive by noon?

4. An IV solution contains 0.0175% of Drug Z, how much of this IV solution should we infuse, if the patient needs 100 mg of Drug Z?
If this solution is infusing at 50 ml/hr, how long will it take take to complete the infusion? Hint: 1mg = 0.001g or ml.

5. A tube-feeding formula is administered to the patient via Gastrostomy at 75 ml/hr. The formula contains 6.5% protein.
How much protein will the patient receive in the entire day, if the feeding must be held (stopped) for 2 hours before and 2 hours after the administration of Dilantin, twice a day?

Answer 1

1. 5% Dextrose in Water means 5g dextrose in 100 ml water.

Rate of infusion of the given solution=50ml/hr

Amount of dextrose in 50ml D5W=2.5g

That means patient is getting 2.5g dextrose in an hour

Therefore the amount of dextrose patient is going to get after 10 hours = 2.5g×10hr = 25g

2. TPN contains 8.25% amino acids

That means 100ml TPN contains 8.25g amino acids

Dose required = 75g

Dose in Hand =8.25g/100ml

Volume of TPN to be infused to get 75g protein= (75g/8.25g) ×100ml=909ml

3. 0.025% of IV solution of drug X =0.028g/100ml

=28mg/100ml

Rate of infusion = 100ml/hr

Total hours infused from 6 am to 12 noon = 6 hours

Total volume administered by noon=100ml×6hrs

=600ml

Amount of drug In 100 ml=28mg

Therefore amount of drug patient get over a period of 6 hours= 28mg×6hours

=168mg

4.a. Solution of 0.0175% of drug z means

0.0175g of drug z in 100ml solution

=7.5mg/100ml (1g=1000mg)

Patient requires 100 mg of drug z.

Therefore the volume of solution to be infused=(100mg/7.5mg) ×100ml= 1333ml

b. If the rate of flow = 50ml/hr

Time required to infuse 1333ml solution=1333ml×50ml/hr

= 24 hours

5. Formula containing 6.5% protein means 6.5g protein in 100 ml formula.

Rate of administration of formula= 75ml/hr

If Formula must be stopped 2 hours before and 2 hours after administration of Dilantin twice a day

Total amount of withholding time =2hours before×2 hours after× 2 times in 24 hours

=8 hours in 24 hour

There fore the remaining time= 24hours-8 hours

=16 hours

Amount of formula administered over 16 hours at a flow rate of 75ml / hour= 75ml×16hours

=1200ml

Formula contains 6.5g protein in 100 ml

Therefore amount of protein in 1200ml formula

=(1200m÷100ml) ×6.5g

=12×6.5

=78g