Question

1. A 12-year-old child is being treated for an intra-abdominal infection post appendectomy. The provider has ordered piperacillin and tazobactam (Zosyn) 200 mg/kg/day q 6 hours IV. The child weighs 98 pounds. How many mg per dose should the child receive? Round your final answer to the nearest whole number.

2. The Zosyn is supplied in a piggyback form containing the full dose in a 100ml bag and is to be infused over 1 hour. What rate do you set the IV pump at?

3. A nurse is caring for a 5-year-old child with a kidney disorder and is calculating the intake and output. The nurse expects that this child should have a minimum output of 2ml urine/kg/hr. The child weighs 42 pounds. What is the minimum output that the child should have over the course of this nurse’s 12-hour shift? Round your final answer to the nearest whole number.

4. A nurse is calculating the required daily maintenance fluid intake of an infant weighing 17 lbs. Using the formula provided in class and in your Wong text on page 690, calculate the daily requirement for this infant. Round your final answer to the nearest whole number.

5. Calculate the daily maintenance fluid requirements for a child weighing 52 pounds. Round your final answer to the nearest whole number.

6. A provider has ordered a child with a staph infection to receive Vancomycin at a dose of 40mg/kg/day to be administered every 8 hours. The child weighs 9600 grams. Calculate the correct pediatric dose for this child. Round your final answer to the nearest whole number.

Answer 1

1. Weight of child = 98 lb or 98 ÷ 2.2 = 44.45 kg

Dose ordered = 200 mg/kg/day

dose frequency = every 6 hourly

Dose for the child = dose ordered x weight of child

Dose for the child = 200 x 44.45 = 8890 mg/day.

This is the dose for per day. To calculate drug amount for every dose divide by 6 (drug frequency)  

drug amount for every dose = 8890 ÷ 6 = 1481.66 or 1482 mg.

Answer = 1482 mg

2. Infusion rate = volume (ml) ÷ time (min)

Volume = 100 ml

Time = 1 hr or 60 min

Infusion rate = 100÷60 = 1.66ml/min

3. Minimum urine output = 2 ml/kg/day

weight of child = 42 lb or 19.05 kg

minimum urine output for child in 12 hours = minimum urine output x weight x 12

Minimum urine output for the child = 2 x 19.05 x 12 = 457.2 ml or 457 ml

Answer = 457 ml

4. weight = 17 lb or 7.7 kg  

Daily maintenance fluid requirement =  100 ml/kg

Daily maintenance fluid requirement = 100 x 7.7 = 770ml

5. Child weight = 52 lb or 23.58 kg

Daily maintenance fluid requirement = 1500 ml + 20 ml per each kg above 20 kg

Dailg maintenance fluid requirement for the child = 1500 ml + (20 × 3.58) = 1571.6 ml or 1572 ml

6. Weight of child = 9600 gm or 9.6 kg

Dose = 40mg/kg/day

Dose frequecy = every 8 hourly

drug dose for each day = dose x weight

drug dose for each day = 40 x 9.6 = 384 mg/day

correct paediatric dose per dose = 384 ÷ 8 = 48 mg/dose