Question

What is the importance of having knowledge about chemical bonding for drug design in the healthcare industry? How will this knowledge help medical workers in their healthcare career? Think of how the world is looking for treatments to relieve symptoms and/or reduce the time of illness due to Covid-19. How does knowledge of chemical bonding aid in this global effort to design effective treatments?

***Address the question of chemical bonding to drug design - not something unrelated like drug interactions or about medications given to patients. Instead, focus on how is chemical bonding used to design effective drugs.***

Answer 1

The concept of chemical bonding in drugs for an effective drug desighn is a very relevent and important aspect and need of the hour considering the current scenario of the COVID-19 pandemic.

Desighning a drug for specific use or action needs chemistry to come in play and impart its effect on the human body in the following ways :-

a}  Type of chemical bonding and polarity affects the solubility of a certain drug and therefore it has a big affect on its absorption rate into the blood.

b} Many of the drugs act in the body by binding to receptors/enzymes . The type of functional groups present will affect this and in turn the effectiveness of the drug.

  

  c} The type of chemical bonding also affects the overall safety profile of the drug, making it to give very less chances ofany negative impact to the body.