Extrinsic asthma occurs when the immune system overreacts to a harmless substance, such as pollen or dust. The body releases an antibody called immunoglobin E (IgE). The release of this antibody leads to inflammation and asthma symptoms
Intrinsic asthma occurs when something other than allergens triggers an immune system response. People are not always able to identify the trigger.
Intrinsic asthma tends to start later in life, is more common in
females, and is typically more severe. The main difference between
the two is the level of involvement of the immune system: In
extrinsic asthma, symptoms are triggered by an allergen (such as
dust mites, pet dander, pollen, or mold).
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