# Clinical picture of bipolar l and bipolar ll
Bipolar l disorder involves period of severe mood episodes from mania to depression.Bipolar ll disorder is a milder form of mood elevation, involving milder episodes of hypomania that alternative with periods of severe depression.
# Risk factors of bipolar disorder
* Having a first degree relative such as parent or siblings,with bipolar disorder
* May be triggered by stressful events,such as the death of loved once or other traumatic event.
* Drugs or alcohol abuse .
* Sleep deprivation and hypothyroidism
# 3 signs and symptoms of bipolar disorder.
There are three types of bipolar disorder they are
* Bipolar l disorder - defined by manic episodes.In this patient have hyperirritable mood , increased psychomotor activity,excessive social extroversion,rapid speech with frequent topic change .Manic symptoms are so severe ,so patient need immediate hospitalization.
* Bipolar ll disorder - defined by depressive episodes and hypomanic episodes.In this patient have lowself esteem , feelings of hopelessness,apathy, difficulty in concentrating or thinking clearly, psychomotor retradation ,sucidual ideation .
* Cyclothymic disorder/ Cyclothymia - defined by periods of hypomanic symptoms as well as periods of depressive symptoms lasting for at least 2 years .In this patient have hyperactivity and physical restlessness, irritability, social withdrawal,lethargy ,deceased productivity, feeling of inadequacy.
# 3 intervention used for mania episode.
*Psychopharamacotherapy
Mood stabilizer,( lithium 900 - 2100mg /day 3divided dose ,carabamazapine 600 - 1800mg /day , sodium valproate 600 - 2600 mg / day ). Other drugs are antipsychotics medications and antianxiety drugs ( eg : diazepam, Clonazepam)
* Electro convulsive therapy (ECT) it is in the case of acute mania .if the patient is not adequately responding to antipsychotics and lithium.
* Therapies
Individual therapy- it is a form of therapies ,which the clieyis treated on a one on one basis with a therapist.
Family therapy- it is a type of psychological counseling that can help family members improve communication and resolve conflict.
Marital therapy- it is a form of psychotherapy with the aim of helping the partners to enjoy a more rewarding relationships.
# Drugs approved for bipolar disorder.
* Mood stabilizer
Lithium, Valpronic acid , carabamazapine,lamotrigine
* Antipsychotics
Clozapine,cariprazine , risperidone,lurasidone ,olanzapine .
* Antidepressants
Selective serotonin reuptake inhibitor, tricyic antidepressants.
# clinical picture of depressive disorder.
* Low sel-esteem
* Over whelming inertia
* Feeling of hopelessness,apathy
* Difficulty in concentrating or in thinking clearly ( without obvious ddisorientation or intellectual impairement)
* Psychomotor retradation
* Anhedonia
* Sucidual ideation.
# Risk factors of depressive disorder
* Genetics- a history of depression in your family may make it more likely for you to get it.
* Death or loss - sadness and greif are normal reaction.some time big stresses can bring serious symptoms of depression like thoughts of sucide or feeling of worthless.
* Conflict- disputes with family or friends may lead to depression.
* Abuse - past physical, sexual or emotional abuse can bring it on , as well
* Life events- even good thoughts could make you depressed.
# Vegetative signs of depression
* Insomnia or hypersomnia
* Fatigue and low energy
* Inattention
* Weight loss and anorexia .
# 3 phases of treatment of major depression.
* Acute phase - remission is induced ( minimum 6-8weeks in treatment), in this phase provide pharmacotherapy alone or both combination of psychotherapy and pharmacotherapy.
* Continuation phase - remission is preserved and relapse prevented ( usually 16-20 weeks in duration) , psychiatric management should continue in this phase .
* Maintance phase - suceptible patient are protected against recurrence or relapse of subsequent major depressive episodes.( Duration various with frequent and severity of previous episodes)
# 3 intervention for depressive treatment
* Cognitive behavioral therapy- focus on present thinking behaviors and communication other than on past experience and is oriented towards problems solving.
* Interpersonal therapy - it focused psychotherapy that centered on resolving interpersonal problems and symptoms recovery
* Psychodynamic therapy - form of therapy with focus on holistic prospective of the client.
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