Supply curve will not change.
The large pharma firm operates in a market structure where it faces a downward sloping demand curve. Profit-maximizing output is determined by equality of marginal revenue (MR) and marginal cost (MC), where MC curve is approximated to be Purdue's supply curve. Since MC is the ratio of change in total cost (TC) to a change in output, an increase in fixed cost does not impact MC, therefore supply function remains unchanged. Profit maximizing output and price will not change, but due to the one-time increase in fixed cost, the relevant period's profit will be lower.
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