The specific rotation of L-alanine in water (at 25°C) is +2.8. A chemist prepared a mixture of L-alanine and its enantiomer, and 3.50 g of the mixture was dissolved in 10.0 mL of water. This solution was then placed in a sample cell with a pathlength of 10.0 cm and the observed rotation was +0.70. Calculate the % ee of the mixture.
mass of L - alanine = m
mass of D-alanine = 3.50 - m
excess mass of L - alanine = m - (3.50 -m)
concentration of L-alanine = 2m - 3.50 / 10
= (0.2 m - 0.35 ) g/mL
observed rotation = specific rotation x l x C
0.70 = 2.8 x 1 x (0.2 m - 0.35)
m = 3
% ee = (excess mass of L- alanine / total ) x 100
= (2 x 3 - 3.5) / 3.50 ) x 100
% ee = 71.4 %
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