Question

The LEAST stable conformational isomer of cis-1-isopropyl-2-methylcyclohexane will have:

A. Both isopropyl and methyl groups in axial positions

B. Both isopropyl and methyl groups in equatorial positions

C. The isopropyl group in an axial position and the methyl in an equatorial position

D. The isopropyl group in an equatorial position and the methyl in an axial position

E. None of the above

Please show work/provide reasoning. Thanks!

Answer 1

Ans :- Option (C) " The isopropyl group in an axial position and the methyl in an equatorial position " is the correct answer.

Explanation :-

For more stable conformation the bigger group that is isopropyl group should be present at the equatorial position and the smaller methyl group should be at axial position.

Now,

For unstable conformation the isopropyl group( bigger group) in an axial position and the methyl (smaller group) in an equatorial position.

Hence, Option (C) is the correct answer.