Question

In terms of liquid to Liquid extractions how does the Solubility of organic compounds, Acid-base theory (explain on the basis of pKa’s) and Manipulating solubility come into play on the reason why it's possible to perform this kind of techique.

Answer 1

Answer:

Liquid to liquid extraction:

Generally the organic compounds ( may liquids) from the aqueous solution extracted by useing organic solvents. If the organic liquid compound is having lower P^ka value, Its acidity is more. For these type of compounds treated with saturated NaHCO3 solution (base treatment) as a result of this the organic acid compound becomes as a sodium salt.

If we extract the aqueous solution with organic solvents the salt can not be extracted, If having of the any other impurities they can be extracted.

Then the aqueous solution is acidified with 1N HCl (Acid treatment) then the compound becomes in to free acid. It can be extracted by useing organic solvents.