Question

Consider the peptide below with the associated pKa values:   Ala-Val-Asp-Lys-His-Arg-Ser-Thr-Asn The peptide has the following pKa...

Consider the peptide below with the associated pKa values:   Ala-Val-Asp-Lys-His-Arg-Ser-Thr-Asn

The peptide has the following pKa values:

C-terminal COOH pKa = 2

Asp pKa = 4

His pKa = 7

N-terminal pKa = 9

Lys pKa = 11

Arg pKa = 12

What is the pI of this peptide?

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