Question

There is the discussion in the literature that succinylcholine is an agonist and some places say it is an antagonist. In addition, some argue that succinylcholine is both agonist and antagonist. Write a defense, including the use of stick figures, for the position that it succinylcholine is both an agonist and antagonist.

Answer 1

Suxamethonium chloride. Suxamethonium chloride, also known as suxamethonium or succinylcholine, is a medication used to cause short-term paralysis as part of general anesthesia.

Suxamethonium is in the neuromuscular blocker family of medications and is of the depolarizing type.Mechanism of action. Depolarizing drugs are agonists at ACh receptors. Succinylcholine is the only depolarizing NMBD in clinical use. It is effectively two ACh molecules joined through the acetate methyl groups.

if we use this medicine in regular use or over doses its act as a antagonist.

An agonist is a chemical that binds to a receptor and activates the receptor to produce a biological response. Whereas an agonist causes an action, an antagonist blocks the action of the agonist, and an inverse agonist causes an action opposite to that of the agonist