The specific rotation for optically pure (S)-(+)- phenylsuccinic acid is reported to be [ α]D =+171 degrees (4.0, acetone). Under the same conditions, the specific rotation for a lab sample of phenylsuccinic acid was found to be +130 degrees. Calculate the optical purity (%ee) of the lab sample and the ratio of (R) and (S) enantiomers.
Solution :-
Specific rotation of pure (S)-(+)- phenylsuccinic acid = [ α]D =+171
Observed specific rotation =+130
Lets calculate the optical purity
Optical purity (ee) = [observed rotation / specific rotation of pure]*100%
=[(+130) / (+171)]*100%
= 76.0 %
Now lets calculate the ratio of the R and S enantiomers
First we need to find the totla percent of the S enantiomer in the sample
% S = [(100 % - 76.0 %)/2]+76.0%
= 88 %
Therefore we have 88 % S enantiomer and (100%-88%) = 12 % R enantiomer
Get Answers For Free
Most questions answered within 1 hours.