Question

In the structure of the K+ ion channel, K+ is distinguished from Na+ due to which...

In the structure of the K+ ion channel, K+ is distinguished from Na+ due to which of the following?

a) a phosphorylation which tags K+ for easy transport.

b) an allosteric interaction with ATP which opens the channel to K+.

c) a narrowing of the channel strips K+ but not Na+ of its waters of hydration.

Science   Chemistry   
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Answer #1

option C.

At the entryways of K+ ion channel there are amino acid residues which help to draw the K+ ions.The ion path begins as water filled wide channel in which ion can retain its hydration shell.Then the channel narrows ,the region of selectivity filter,here ion have to give up hydrated water molecules..In the peptide backbone of the selectivity filter there is Carbonyl oxygens.This Carbonyl oxygens interact and stabilize the K+ ions passing through.This interaction is not possible with sodium ion.This is why K+ filter in ion selective

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