Draw the structure of the peptide DTLH, showing the backbone and side-chain atoms, at its isoelectric point. Draw the molecule on the canvas by choosing buttons from the Tools (for bonds and charges), Atoms, and Templates toolbars. Draw peptide molecule as zwitter ion.
1- DTLH: Asp-Thr- Leu-His
At pH= 6, Aspertate’s side chain is –vely charged
Histidine’s side chain is vely charged
N-terminal amino group is +vely charged
C-terminal carboxyl group is –vely charged
Hence, total charge is 0
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