Question

How many other heterodisaccharides can galactose and glucose form? Explain.

Answer 1

I know three Hetero disaccharides like 4-O-β-D-glucopyranosyl-6-deoxy-D-glucose (Glc-6-deoxy-Glc), 4-O-β-D-glucopyranosyl D-mannosamine (Glc-ManN), 4-O-β-D-glucopyranosyl-D-mannose (Glc-Man).

Were synthesized from equimolar amounts of

6-deoxy-glucose and α-D-glucose-1-phosphate (G-1-P),

D-mannosamine and α-D-glucose-1-phosphate (G-1-P), and

D-mannose and α-D-glucose-1-phosphate (G-1-P), respectively,

The yields were 60%, 10% and 50% based on the initial amounts of 6-deoxy-D-glucose, D-mannosamine and D-mannose, respectively.

The structures of disaccharides were confirmed by NMR and mass spectroscopy analysis.