Question

For questions 7 and 8, imagine that we dissolve a mixture of the compounds (3-nitrobenzoic acid, 2-naphthol, and 1,4-dimethoxybenzene) in diethyl ether. We then add aqueous sodium hydroxide into the mixture and place the solution into a column.

7. Which layer will elute first?

A. Aqueous

B. Organic

C. Other (Specify) _________________________

8. Which compounds (if any) would you expect to find in the first layer to elute from the column?

(Circle all that apply)

A. 3-nitrobenzoic acid

B. 2-naphthol

C. 1,4-dimethoxybenzene

9. Provide one property of the column, compound mixture, or solvent that would improve separation on the column.

___________________________________________

10. Using a more polar solvent would (circle one)

A. improve

B. worsen

C. have no effect on separation in this experiment.

Answer 1

7. Which layer will elute first?

B. Organic

Because always non polar solvents are coming first in the coulmn since column is packed with polar molecules

8. Which compounds (if any) would you expect to find in the first layer to elute from the column?

C. 1,4-dimethoxybenzene

Other 2 compounds will become salt with NaOH

9. Provide one property of the column, compound mixture, or solvent that would improve separation on the column.

Column should be packed tighter and longer will give good separation

If compounds mixture having large Rf value that will lead to good separation

Solvent polarity should be increased slowly.

10. Using a more polar solvent would (circle one)

B. worsen

All compounds will come together