Question

In an aspirin tablet.....What would be the consequence of competing equilibria, such as from other ingredients...

In an aspirin tablet.....What would be the consequence of competing equilibria, such as from other ingredients in the tablet, on your results? (% of aspirin in tablet, concentration of aspirin...) What if there were several pain relievers in the same tablet? How could the error from these interferences be minimized?

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Answer #1

Aspirin is a weak acid that is more soluble in alkaline solution (Sodium hydroxide (NaOH).

To find the % and concetration of Aspirin can be determined through back titration method.

Competing equilibrium will change if the amount of NaOH consumed more in back titration.

Multiple pain relievers in a single tablet will decrease the amount of sodium hydroxide consumed in the titration reaction with aspirin if the pain relievers are weak acids likeaspirin

The errors from these interferences can be corrected by separating the different pain relievers using techniques like high performance liquid chromatography (HPLC) .

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