Question

Imagine that inside a cell the [creatine phosphate] = 3.5 mM, [creatine] = 0.6 mM, and [Pi] = 4.3 mM. Furthermore, imagine that the pH inside the cell is 7.4. Given that ΔG°′ for creatine phosphate hydrolysis is -10.3 kcal/mol, what is the ΔG for creatine phosphate hydrolysis inside the above-described cell, which is at 37 °C? Report your answer in kcal/mol to the nearest tenths. Hint: you might wish to consult the chapter in our text that discusses thermodynamics.

Answer 1