Question

A reconstituted Ampicillin Suspension has a shelf life of 14 days when stored in the refrigerator (5°C). If the product is left at room temperature (25°C) after preparation, how long it can be kept and used safely and effectively? (Q₁₀ = 3)

Answer 1

In spite of the fact that the marks on each of the commerical penicillin items tried show that the reconstituted items might be put away in a cooler for 14 days without critical loss of intensity, just a single penicillin item still met 90% of name guarantee (negligible strength necessity of the United States Pharmacopeia for dry powder). All ampicillin items tried were steady when put away at the conditions suggested by the producers, yet the trihydrate frames displayed more noteworthy soundness than the anhydrous structures, likely as a result of the more fast disintegration rate of anhydrous ampicillin.