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3. What do you mean by “carrier-linked prodrugs”? Classify with appropriate examples.

3. What do you mean by “carrier-linked prodrugs”? Classify with appropriate examples.

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Answer #1

Career linkes pro drugs are the active drugs which are linked to the removable careers which are usually hydrolyzable groups such as amides, esters etc.

Their classified as

Bipartate prodrug, one carrier which is attached to one drug. Example prednisolone sodium phosphate

Tripartate prodrug, one drug which is connected to carrier through linker. Example pivampicillin

Mutual drug, two drugs which are synergetic to each other are attached. Example sultamicillin

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