Question

Why might TLC not be the best technique to determine the identity of a compound?

Why might TLC not be the best technique to determine the identity of a compound?

Homework Answers

Answer #1

In TLC, the Rf value of spot of compound to be determined is compared with Rf value of spot of standard. If the two Rf values match, then we can say that the compound to be determined is probably the standard spotted. But it is only approximate conclusion. It may happen that two different compounds have same Rf value on TLC plate. Hence, we will identify these two different compounds as same compound which is not correct. Hence, TLC might not be the best technique to determine the identity of a compound. When two compounds have same Rf value on TLC, we can say that these compounds have similar polarity. They may have different structure.

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