Question

Based off of the one letter abrev. for the amino acids, are any of these peptide chains hydrophobic? Please explain why or why not ***each peptide chain has a NH3+ at the N-terminus and COO- at the C-terminus***

1 = MWQINAGP....Met, Trp, Gln, Ile, Asn, Ala, Gly, Pro

2 = GGVYAR..... Gly, Gly, Val, Tyr, Ala, Arg

3 = HIFPCK ......... His, Ile, Phe, Pro, Cys, Lys

Answer 1

Hydrophobic compounds are water repellent molecules; generally molecules dissolve in water by forming hydrogen bond. but some aminoacids are water repellent or hydrophobic, they are are glycine (Gly), alanine (Ala), valine (Val), leucine (Leu), isoleucine (Ile), proline (Pro), phenylalanine (Phe), methionine (Met), and tryptophan (Trp).

Now, look qustions, in 1st peptide, methionine is at one end, means that part will act as an hydrophobic part with Trp. another end also hydrophobic because of the presence of Glycine, proline.

2nd compound, Glycine and valine end is hydrophobic

in 3rd one, same way you can apply. i hope you got the answer