Question

Mechanism of Bischler-Napieraleski synthesis in step by step synthesis.

Mechanism of Bischler-Napieraleski synthesis in step by step synthesis.
Science   Chemistry   
0 0
Add a commentTranscribed image text
Next >

Homework Answers

Answer #1

The Bischler Napieralski reaction is an intramolecular electrophilic aromatic substitution reaction which allows the cyclization of β- arylethylamides. There are Two types of mechanism for the reaction. The mechanism 1 involves a dichlorophosphoryl imine ester intermediate, and mechanism 2 involves a nitrilium ion intermediate. The reaction is carried out in refluxing acidic conditions and requires a dehydrating agent. POCl3 is used for this purpose.

0 0
Know the answer?
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for?
Ask your own homework help question
Similar Questions
a) suggest a step by step synthesis of Sudan II molecule b) propose a mechanism for...
a) suggest a step by step synthesis of Sudan II molecule b) propose a mechanism for each step. c) predict the structure of the conjugate acid of Sudan II with mechanism.
What is the rate-limiting step of 1-Bromobutane Synthesis by the SN2 Mechanism? Provide an explanation.
What is the rate-limiting step of 1-Bromobutane Synthesis by the SN2 Mechanism? Provide an explanation.
Please draw the detailed reaction mechanism for the synthesis of epoxycyclohexane from cyclohexene
Please draw the detailed reaction mechanism for the synthesis of epoxycyclohexane from cyclohexene
What is the mechanism of synthesis of phosphoribosyl pyrophosphate and what role does it play in...
What is the mechanism of synthesis of phosphoribosyl pyrophosphate and what role does it play in the cell?
Draw and explain the mechanism for the synthesis of dimethylmaleate (using Maleic anhydride, methyl alcohol and...
Draw and explain the mechanism for the synthesis of dimethylmaleate (using Maleic anhydride, methyl alcohol and sulfuric acid as the catalyst). Draw and explain the reaction mechanism for halogen-catalyzed cis-trans isomerization of dimethylmaleate.
The following three step mechanism has been proposed for this reaction: Step 1: A + B...
The following three step mechanism has been proposed for this reaction: Step 1: A + B <--> G fast Step 2: A + G --> E + D slow Step 3: E + 2C --> 2D + F fast Determine the rate law predicted by the mechanism. Identify any intermediates shown. The experiemental rate law was determined to be Rate = [A]2[B]. Is this mechanism valid?
Can you draw the mechanism for the synthesis of spingomyelin and include reactants, products and electron...
Can you draw the mechanism for the synthesis of spingomyelin and include reactants, products and electron movement? Thanks!
using the following mechanism : step 1. NO2 + F2 ---> NO2F + F step 2....
using the following mechanism : step 1. NO2 + F2 ---> NO2F + F step 2. NO2 + F ---> NO2F list all intermediates found in the mechanism. please explain, will rate
(Solid Phase Peptide Synthesis) What is the mechanism of TFA cleavage of peptide from the solid...
(Solid Phase Peptide Synthesis) What is the mechanism of TFA cleavage of peptide from the solid support resin? Explain.
What are substances that are made in one step of a mechanism and then used in...
What are substances that are made in one step of a mechanism and then used in a later step called
ADVERTISEMENT
Need Online Homework Help?

Get Answers For Free
Most questions answered within 1 hours.

Ask a Question
ADVERTISEMENT