Question

What are two reasonable mechanisms for the reaction of benzonitrile and tert-butyl alcohol under acidic conditions?

What are two reasonable mechanisms for the reaction of benzonitrile and tert-butyl alcohol under acidic conditions?

Homework Answers

Answer #1

Ritter reaction is the acid-induced nucleophilic addition of a nitrile to a carbenium ion, followed by hydrolysis to the corresponding amide.

The reaction of benzonitrile and tert-butyl alcohol under acidic conditions is:

C6H5-CN + C(CH3)3OH → C6H5-CO-NH-C(CH3)3

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